Mr. Chhuttan Lal Meena
| Grant Category: | Fulbright-Nehru Doctoral and Professional Research Fellow |
| Field of Specialization: | Medicinal Chemistry |
| Name: | Mr. Chhuttan Lal Meena |
| Official Address and Designation: | Research Scholar
National Institute of Pharmaceutical Education and Research (NIPER) Department of Medicinal Chemistry Block-B, B-210, S.A.S. Nagar, Phase-10 Mohali, Punjab 160 062 |
| Telephone (O): | 91-172-2292024 |
| E-mail: | chhuttan_pharma@yahoo.co.in |
| Duration of Grant: | Nine Months |
| Project Title: | Synthesis of New Thyrotropin- Releasing Hormone (TRH) analogues |
| Abstract of Project : | |
| Thyrotropin-Releasing Hormone (TRH) is a key hormone responsible for proper brain-body coordination. It has been investigated for the possible applications in the treatment of epilepsy, Parkinson's disease and other Central Nervous System (CNS) disorders. TRH acts on two sub-types of receptors: TRH-R1 and TRH-R2. The activation of TRH-R1 receptor leads to analogues with endocrine effects of TRH; while activation of TRH-R2 receptor leads to analogues displaying selective CNS effects such as epilepsy and Parkinson's disease. The objective of my research during my Fulbright grant is to develop TRH analogues with selective TRH-R2 receptors. I have synthesized several TRH analogs with good CNS activity. I hope my research will ultimately would lead to the discovery of small neuroprotective peptides useful in the treatment of diseases like epilepsy, Parkinson's, Alzheimer's and several other motor neuronal disorders. | |
| Academic Background : | |||
| Ph.D. | Medicinal Chemistry | NIPER-S, Mohali | 2007-Till date |
| M. Pharm. | Medicinal Chemistry | NIPER-S, Mohali | 2006 |
| B. Pharm. | Pharmaceutical Sciences | Mohan Lal Sukhadia University, Udaipur | 2002 |
| Professional Background: | |||
| Senior Research Fellow | NIPER-S, Mohali | 2008-Till date | |
| Junior Research Fellow | NIPER-S, Mohali | 2006 – 2008 | |
| Research Associate | Jubilant Chemys Ltd., Noida | 2006 – 2006 | |
